Steam game

Genome Guardian 2

COMBINE WEAPONS in the microscopic shooter with macroscopic depth. BUILD YOUR NANOBOT from hundreds of parts. SURVIVE the microbial onslaught once more in this psychedelic dive to the Abyss, full of mutations, minerals, anomalies and powerup polyps. SHMUP mode turns it into a vertical shoot 'em up!

$15.99 March 5, 2026

By Alpherior

Windows Controller: full
View on Steam
Genome Guardian 2 - Alpherior. Popular. Released March 5, 2026
Screenshot of Genome Guardian 2 gameplay showing in-action mechanics Screenshot 2 of Genome Guardian 2 - additional gameplay view Screenshot 3 of Genome Guardian 2 - more gameplay footage Screenshot 4 of Genome Guardian 2 - final gameplay screenshot

Overview

About this game

Dive back into the microscopic world, radiating with bioluminescent life and unspeakable horrors.

Research permanent upgrades to survive a variety of microbes & modes in this massively expanded follow-up to Genome Guardian.

Build your own biomechanical death machine from different parts to define how it shoots, behaves & moves!

Make stationary turrets, psychic water sprinkler motorbikes, or maybe a dual-wielding fidget spinner Gundam.

  • Easily recreate your favourite turrets from the first game…or combine em' all into one frankenstein monstrosity

  • Save/Load 24 loadouts

  • Paint & Pattern customization

Pair DNA nucleotides A (rapidfire), C (precision), G (spread), T (explosive) to discover 70 hybrid bioweapons!

  • Shotgun + Bomb mix explosives with spread for Blast Shotgun!

  • SMG + Pistol make an accurate, fast-firing Scout Rifle!

  • Blast Shotgun + Scout Rifle = something a whole lot crazier!

  • 20-minute runs you can save & resume at any time + improved Endless Mode

  • Complete side objectives during runs for extra cash

  • Mine mineral deposits for resources

  • Trigger powerful Gadget active abilities

  • Test discovered weapons in the Database

  • 100 bassy electronic tunes with in-game Jukebox accessible any time + Streamer Mode

  • Auto aim/fire toggles

  • Localization in 10 languages

  • Full rebinding for keyboard & gamepad

  • 400% better performance/framerate on high & low-end PCs

  • Accessibility for colourblindness, motion sickness & arachnophobia

  • 100 Steam achievements

  • Cloud Save

  • Plays great on Steam Deck!

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